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MAMMAL

Drug–target interaction (pKd)

Predict drug–target binding affinity as pKd (−log₁₀ Kd). Higher pKd means stronger predicted binding. The model is CPU-bound; use a client timeout of at least 60 seconds.

post/api/v1/mammal/dti

Request body

target_seqstring required

Target protein amino-acid sequence (single-letter codes).

drug_seqstring required

Drug structure in SMILES notation.

norm_y_meannumber

Optional. Normalization mean override.

norm_y_stdnumber

Optional. Normalization standard-deviation override.

Response

DTI prediction.

Example response

{
  "data": {
    "pKd": 5.4932751
  }
}