(ESM3) Generates an output track conditioned on inputs

You may have access to additional, private models as well. These will be visible on the Rate Limits page under the Developer Console

Disclose potential sequences of concern. For approved users, such sequences will not go through additional safety filtering. Reach out if you are interested in using this.

Track to generate: sequence, structure, secondary_structure, sasa, or function.

Unmasking schedule for generation. Controls the number of tokens to unmask during each round of iterative generation.

Unmasking strategy to use. Controls which tokens to unmask during each round of iterative generation. 'random' will unmask a correct number of tokens randomly. 'entropy' will unmask the tokens with the lowest logit entropy first. Default was random. Updated on 02/14/2025.

Number of steps for generation. There is diminishing return for decoding steps more than 20. Note that this needs to be less than or equal to the sequence length. Default was 8. Updated on 02/14/2025.

Temperature for sampling. Default was 1.0. Updated on 02/14/2025.

Whether temperature should be annealed during generation. Default was False. Updated on 02/14/2025.

Top-p sampling.

Use coordinates instead of structure tokens as generation conditioning.

Only compute the RMSD of the backbone atoms. Affects the returned crmsd.

You may have access to additional, private models as well. These will be visible on the Rate Limits page under the Developer Console

ISO formatted date time

Indicate that the returned sequence may be of potential concerns.