---
title: "ClinTox clinical-trial toxicity"
method: POST
path: "/api/v1/mammal/clintox"
tags: ["MAMMAL"]
---

# ClinTox clinical-trial toxicity

`POST /api/v1/mammal/clintox`

Predict clinical-trial toxicity for a compound. The model is CPU-bound; use a client timeout of at least 60 seconds.

## Request body

- ClintoxRequest
  - `smiles` string, required — Compound structure in SMILES notation.

## Response `200`

ClinTox prediction.

- object
  - `data` ClintoxResult
    - `pred` 0 | 1 — 1 = toxic / likely to fail trials, 0 = not toxic.
    - `score` number — Raw positive-class score.

## Other responses

- `401` — Missing, invalid, or revoked API key.
- `422` — Missing or invalid request body fields.
- `429` — Rate limit exceeded (100 requests/hour per key). Includes a Retry-After header.

---

[API](https://skmtc.net/curecancerwithai/apis/cure-cancer-with-ai-public-api.md) · [All operations](https://skmtc.net/curecancerwithai/apis/cure-cancer-with-ai-public-api/llms.txt) · [OpenAPI document](https://skmtc-service-staging.skmtc.workers.dev/v1/apis/curecancerwithai/cure-cancer-with-ai-public-api/revisions/fd99aa2f2fd5/schema)